CD133-APC

C15190

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CD133, also known as AC133 or PROML1, is a 5-transmembrane glycoprotein of 120kDa belonging to the prominin family. It is mainly expressed on primitive cell populations such as CD34 hematopoietic stem and progenitor cells, neural and endothelial stem cells. In association with CD309 (KDR or VEGFR-2), CD133 allows the specific detection of endothelial progenitor cells. CD133 function is unknown although a naturally occurring mutation is associated with degenerative disease in the retina of affected patients.

Specifications

Target Species Human
Specificity CD133
Other Names AC133, PROML1, prominin-like 1, hematopoietic stem cell antigen
Fluorochrome APC
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone W6B3C1
Isotype IgG1 Mouse
Clone Description The clone W6B3C1 was assigned to CD133 during the Seventh HLDA Workshop on Human Leukocyte Differentiation Antigens. Similarly to AC133/1 clone, it recognizes the epitope 1.

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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.