DURAClone IM TCRs
Le cellule T mature esprimono recettori delle cellule T (TCR) che permettono il riconoscimento a bassa affinità degli antigeni legati alle molecole del complesso maggiore di istocompatibilità (MHC). Sono note due forme di TCR che consistono in eterodimeri di catene proteiche α e β variabili o catene proteiche γ e δ. La proporzione di queste due sottopopolazioni è considerata importante nell'immunità e nella tolleranza con meccanismi ancora in fase di studio. Il pannello DURAClone IM TCRs permette di valutare l'espressione della catena proteica TCR αβ e TCR γδ e di rilevare le sottopopolazioni Vδ1+ e Vδ2+ tra le cellule T TCRγδ+. Utilizza la tecnologia dei reagenti a secco che facilita i vostri processi di lavoro.
- Combinazione di 9 marcatori in combinazioni fluorocromatiche che forniscono una robusta identificazione della popolazione, compresi CD3, CD4, CD8, CD45, HLA-DR, TCR αβ, TCR γδ, TCR Vδ1, TCR Vδ2
- Pannello di anticorpi preformulato in un test unificato che elimina il cocktail di anticorpi
- 25 test per kit, compresi 3 kit di compensazione con coloranti tandem abbinati al lotto
Adatto solo all'utilizzo in ricerca. Non adatto all'utilizzo in procedure diagnostiche.
Features
Expert Panels
- Proven marker combination to identify the relative proportions of TCR types in the T cell compartment
- Open channels to add drop-in markers to modify for different research questions
- Designed for assay precision and lot-to-lot consistency
Efficiency
- Eliminate time spent in titrating different antibody lots
- Avoid waste that comes from preparing cocktail master mix
- Simplify inventory management
Consistency
- Unitized assays eliminate error prone pipetting steps
- Includes lot matched tandem dyes for compensation controls for improved accuracy
- Dry format maintains reagent performance better than liquid under stress conditions
Easy to Use
- Ready to use assay with verified panel design
- Includes sample preparation and staining procedure
- Streamlined workflow, just add sample, incubate, wash and acquire
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