Immunotherapy

Immunotherapy involves understanding and harnessing the relationship between the immune system and cancer cells to combat oncogenesis. There are many different potential immunotherapeutic approaches, including cell-based strategies such as adoptive cell transfer, receptor pathway-based strategies such as checkpoint inhibition, and agent-based approaches such as antibody therapy. Genetic engineering can be incorporated into all of these approaches. Gene editing can be used to modulate receptor expression levels, induce the production of certain molecules, change cellular phenotypes, or alter the general intensity of the immune response.

Immunotherapy Shows Renewed Promise for Cancer Therapies

Per saperne di più
Pediatric Immunotherapy
About CRISPR
CAR-T Cells
Explore Viral Vectors
Producing Viral Vectors
Characterizing Viral Vectors

Content and Resources

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How can nanoparticles be used for immunotherapy? We examine how nanoparticles can be used for immunotherapy as well as in other research areas
How do oncolytic viruses target cancer cells in immunotherapy? We examine how oncolytic viruses target cancer cells in immunotherapy and how genetically modified viruses apply
Are there different CRISPR-associated system (Cas) proteins? Discussion around how different protein families associate with CRISPR (clustered regularly interspaced short palindromic repeats)
How is the CAR receptor introduced to the T cell? We explore how the CAR receptor is introduced to the T cell and the delivery methods that are involved
What antigens can a CAR-T cell target? Discussion around what antigens a CAR-T cell can target and for what purposes